Akina
PolyVivo

Applications

Nano-immunotherapy: Use of polymers in immunotherapy by delivery of biologicals as a treatment for cancer and other diseases. (1, 2)

Stem-Cell tissue engineering: Use of 3DCellMaker as well as other polymers for stem-cell growth and development.

3D-gelprinting or bioprinting: Use of thermogels for bioprinting applications. (1)

Other Applications: others

Categories

Block Copolymers

Biodegradable hydrophilic block copolymers. These polymers are block copolymers of hydrophillic, biocompatible poly(ethylene glycol) (PEG), and biodegradable polymers such as poly(lactide-co-glycolide) (PLGA), poly(caprolactone) (PCL), and poly(lactide) (PLA).

Ideal for delivery of poorly soluble drugs such as paclitaxel. PolyVivo polymers can be used for a wide variety of drug delivery platforms, including polymer micelles, thermoreversable hydrogels and other formulations.

Intermediates

Contain reactive or activatable groups for you to customize for your application. Have a specific ligand you want to try out? Have a new targeting strategy? Bring your ideas to the benchtop and animal models quickly by starting with one of Akina's intermediates.

Modified PEGs

Polymers built with polyethylene glycol.

Monomers

Components used to synthesize a variety of polymers, with no required minimum on the order.

Other

This includes regular PLGA, PLA,bio-inspired and other materials which don't fit into the above categories. Keep in mind on these polymers we don't lock you in to any minumum orders. Purchase as much or as little as you like.

Specialty Polyesters

Biodegradable non-block polymers that can be used for water solubilization or solid phase drug delivery.

Linear Polesters

Biodegradable non-block polymers (Also see: Polyesters arranged by weight, endcap, LG ratios and chirality).

Fluorescent Polymers

"So where did my polymer delivery system go?" is a fairly common question in research. These fluorescent conjugated polymers can be easily seen under most fluorescent microscope systems and other related fluorescent based techniques. Spot and identify your polymers with ease by fluorescence.


The polymers shown are of research grade and are excellent tools for developing drug delivery technology.

For technical questions please view our polymer FAQ page or our technology blog. Thermogelation test results performed at Akina can be seen for products below

Technical Information

The following information is supplemental data for Polyvivo polymers. Note that the polymer chemical analysis information can be accessed by clicking the catalog number of the product in the online catalog.

White Papers and Videos

Paper Catalog Link
White Paper: Passive dissolution of Coumarin-6 into water by PolyvivoPDFResults for 26 polymers: AK009 AK009D AK012 AK019 AK023 AK024 AK030 AK035 AK036 AK044 AK046 AK047 AK048 AO001 AO004 AO005 AO014 AO016 AO017 AO018 AO019 AO020 AO021 AO023 AO026 AO031
Blog video: strength and elasticityAP015—Poly(L-lactide-co-caprolactone) LA:CL 50:50
(Mn 75,000-85,000 Da) L
Blog video: Thermogel InjectabilityAK036—Methoxy poly(ethylene glycol)-b-poly(caprolactone) (Mw ~750:2,500 Da)
Research: Microfluidic Platform for Combinatorial Synthesis and Optimization of Targeted Nanoparticles for Cancer TherapyPDFAK010—Methoxy poly(ethylene glycol)-b-poly(lactide-co-glycolide) LG 50:50 (w:w)
(Mw ~5,000:10,000 Da)
Storage stability of PLCL-PEG-PLCL thermogel as aqueous solutionPDFAK109—Poly(lactide-co-caprolactone)-b-Poly(ethylene glycol)-b-Poly(lactide-co-caprolactone) (~1700-1500-1700 Da, 60:40 CL:LA)
White Paper: Thermogel Mixtures impact on RheologyPDFAK019—Poly(lactide-co-glycolide)-b-poly(ethylene glycol)-b-poly(lactide-co-glycolide) LG 50:50 (w:w)
(Mw ~1,500:1,500:1,500 Da)
WhitePaper: AI057 viscosity in waterPDFAI057—Poly(N-isopropylacrylamide)-N-hydroxysuccinimide endcap (Inherent viscosity (I.V.) = 0.2-0.5 dL/g in methanol at 25°C)
WhitePaper: AO23 cold viscosityPDFAO023—Poly(N-isopropylacrylamide-co-acrylamide) 95:5 NIPAM:AM
WhitePaper: In-vivo imaging with PolyVivo AV006 (PLGA-FPI749)PDFAV006—Poly(lactide-co-glycolide)-FPI749 LG 50:50
FPI749 endcap
Flamma Fluor near-IR conjugated
(Mn 20,000-30,000 Da)
WhitePaper: PolyVivo AO19 pH and temperature sensitivePDFAO019—Poly(dimethylaminoethyl methacrylate-co-methoxy poly(ethylene glycol)) 95:5 DMAEMA:mPEG
WhitePaper: Sensitive to both pH and temperaturePDFAO014—Poly(N-isopropylacrylamide-co-acrylic acid) 95:5 NIPAM:AA
WhitePaper: Solubilization of a drug (AK09D)PDFAK009D—Poly(ethylene glycol)-b-poly(D,L-lactic acid)-decyl (Mw ~2,000:2,200 Da)
WhitePaper: Thermal properties mPEG-PCL polymersPDFAK001—Methoxy poly(ethylene glycol)-b-poly(caprolactone) (Mw ~2,000:5,200 Da)
WhitePaper: Thermogel speed of mixed PolyVivo AK019 and AK012PDFAK012—Poly(lactide-co-glycolide)-b-poly(ethylene glycol)-b-poly(lactide-co-glycolide) LG 50:50 (w:w)
(Mn ~1,000:1,000:1,000 Da)
WhitePaper: Thermogel Users GuidePDFAK012—Poly(lactide-co-glycolide)-b-poly(ethylene glycol)-b-poly(lactide-co-glycolide) LG 50:50 (w:w)
(Mn ~1,000:1,000:1,000 Da)
WhitePaper: Thermogels mixed with biocomponents for 3D cell scaffoldPDFAO025—Stearate-modified methyl cellulose Hydrophobically modified thermogel
WhitePaper: Thermogels mixed with biocomponents for 3D cell scaffoldPDFAO026—Poly(Poloxamer 407)-methylene-diphenyl-di-isocyanate linked
WhitePaper: Thermosensitive nanoparticles AO034 loaded with Coumarin-6PDFAO034—Poly(N-vinylcaprolactam-co-methylmethacrylate) 90:10 VCL:MMA
(Inherent Viscosity (I.V.) = 0.3-0.7 dL/g in ethanol at 30° C)
WhitePaper: Using AK01 to form poorly soluble drug loaded liposomesPDFAK001—Methoxy poly(ethylene glycol)-b-poly(caprolactone) (Mw ~2,000:5,200 Da)
WhitePaper: Viscosity and Thermal Properties (AK12)PDFAK012—Poly(lactide-co-glycolide)-b-poly(ethylene glycol)-b-poly(lactide-co-glycolide) LG 50:50 (w:w)
(Mn ~1,000:1,000:1,000 Da)

Solubility

Download this PDF chart PDF showing what dissolves in what. chart

DSC Curves

AK Series AP Series

 


Intrinsic Viscosity

Intrinsic viscosity of select products determined at 25°C using dichloromethane solvent.

Catalog Number Lot Number Intrinsic Viscosity
(dL/g)
AV008 60805BPR-B 0.558
AK001 30412SMS 0.834
AK002 40821SJH 0.449
AK003 50529FAJ 0.236
AK012 60812SMS 0.237
AO032  60819BPR-A 0.719
AV004 60801DWW-A 0.321
AV027 60805BPR-A 0.428
AP124 60817AHT-A 0.975

Shipment in Box

Ordering Information

PolyVivo polymers are available for sale. Please browse our catalog and purchase on-line. To place an order off-line please contact us to check on availability and to obtain a quotation. Payment via credit card may be made directly to PolySciTech® or through PayPal. For technical questions please view our polymer FAQ page or our technology blog.

Discounts and Coupons

MSDS

 

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