Akinalytics
Polymer Blog
PLGA/PLA Standards
Method Matters
One of the key parameters for a good standard is determination of properties by multiple methods. This is why we provide data from multiple methods so you can be confident in the standards properties. The table below shows a breakdown of data obtained by multiple methods for example standard lots.
Table 1. GPC results from both GPC-4D system and GPC-external standard for indicated polymers
| HNMR | C13NMR | GPC-TD | GPC-ESs | |||||
|---|---|---|---|---|---|---|---|---|
| LA:GA ratio | Rcms | Mn (Da) | Mw (Da) | PDI (Mw/Mn) | Mn | Mw | PDI | |
| PLA 100L-H 180302RAI-A |
100:00:00 | NA | 103,200 | 132,700 | 1.286 | 104,474 | 176,477 | 1.69 |
| PLA 100L-M 180306FAJ-A |
100:00:00 | NA | 24,900 | 33,900 | 1.361 | 34,998 | 53,429 | 1.53 |
| PLA 100L-S 180312FAJ-A |
100:00:00 | NA | 8,142 | 15,890 | 1.952 | 9,350 | 13,829 | 1.48 |
| PLGA 50L-M 180406RAI-A |
50:50:00 | 0.79 | 16,280 | 23,790 | 1.461 | 24,121 | 34,975 | 1.45 |
| PLGA 50L-S 180329RAI-A |
51:49:00 | 0.8 | 5,834 | 8,303 | 1.423 | 8,415 | 12,523 | 1.49 |
| PLGA 75L-H 180313RAI-B |
71:29:00 | 1.69 | 76,170 | 96,330 | 1.265 | 97,812 | 141,117 | 1.44 |
| PLGA 75L-M 180323RAI-A |
72:28:00 | 2.27 | 16,290 | 25,370 | 1.558 | 24,595 | 37,973 | 1.54 |
| PLGA 75L-S 18041RAI-A |
78:22:00 | 2.63 | 12,180 | 17,830 | 1.463 | 20,557 | 28,889 | 1.4 |
