Frosta is protected under patent: Fu, Yourong, Chaul Min Pai, Sang Yeob Park, Gun Seomoon, and Kinam Park. "Highly plastic granules for making fast melting tablets." U.S. Patent 7,749,533, issued July 6, 2010. This technology is available for licensing. 

Frosta® Tablet Technology

Akina has developed a new fast-melting tablet technology called Frosta®. In the mouth, a Frosta® tablet melts in about 10 seconds for easy swallowing. The tablets have been used quite effectively for easy administration of drugs to the elderly and to children.
 

Cost-effective and Strong The Frosta® approach utilizes conventional wet granulation processing and tablet machines, for cost-effective production of fast-melting tablets. Frosta® tablets are strong, with friability much less than 1%, and are stable in an open air environment.
 

Easy to Make Conventional tablet machines are used for production of Frosta® tablets, and no other special instruments are necessary. Because production of the Frosta® fast-melting tablets is not any more expensive than making conventional tablets, the Frosta® processing technology can be used for almost any drugs and dietary supplements.
 

Examples of Frosta® fast-melting tablet payloads

• aspirin
• loratadine
• folic acid / vitamins
• antacids

The unique Frosta® processing allows use of drugs that are in aqueous solution. The cost of making fast-melting tablets by Frosta® technology is lower than by any other existing technologies.
 

Samples Available If you have any drugs or dietary supplements to load into Frosta® fast-melting tablets, please contact us at info@akinainc.com. Fast-melting tablets are also called fast-dissolving, fast-disintegrating and fast-dispersing.
 

Product Demonstrations

Fast-dissolving tablet examples for energy, nutrition and travel.

Video

Key Benefits

• Fast-melting in the mouth: Melting within 5~20 seconds for easy swallowing.
• Extremely cost effective: The same as making conventional tablets.
• Simple processing: One-step wet granulation processing before making tablets.
• Strong mechanical property: Friability less than 1%.
• Multi-tablet packaging possible: Dozens of tablets in one bottle.

Publications

Fu, Yourong, Seong Hoon Jeong, and Kinam Park. “Fast-melting tablets based on highly plastic granules.” Journal of controlled release 109, no. 1 (2005): 203-210.
 

Jeong, Seong Hoon, Yuuki Takaishi, Yourong Fu, and Kinam Park. “Material properties for making fast dissolving tablets by a compression method.”Journal of Materials Chemistry 18, no. 30 (2008): 3527-3535.
 

Fu, Yourong, Chaul Min Pai, Sang Yeob Park, Gun Seomoon, and Kinam Park. "Highly plastic granules for making fast melting tablets." U.S. Patent 7,749,533, issued July 6, 2010.
 

Jeong, Seonghoon, Susumu Kimura, Yourong Fu, and Kinam Park. "Fast-melting tablets having taste-masking and sustained release properties." U.S. Patent Application 11/267,568, filed June 1, 2006.